Human ZacN Receptor

Synonyms:

ZAC, ZAC1, L2

Cat. No.:

CSH0301MP pdf (datasheet)

Quantity/Size:

10 mg

Price:

$1,695.00 BUY

Description:

ZAC forms a cation-permeable ligand-gated ion channel of the "Cys-loop" superfamily. The ZAC gene is present in humans and dogs, however no ortholog has been detected in rat or mouse genomes. ZAC mRNA is expressed in prostate, thyroid, trachea, lung, brain (adult and fetal), spinal cord, skeletal muscle, heart, placenta, pancreas, liver, kidney and stomach. The endogenous ligand for ZAC is thought to be Zn2+, although ZAC has also been found to activate spontaneously. The function of spontaneous ZAC activation is unknown.

The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.

Uniprot ID:

Q401N2

Data PDF:

CSH0301