Mouse Anti-Human Ang-2 Clone B-G60 Azide Free mAb

Molecule:

Angiopoietin-2

Synonyms:

Angiopoietin-2, ANGP2

Species:

Human

Cat. No.:

CDM081 pdf (datasheet)

Quantity/Size:

500 ug

Price:

$650.00 BUY

Concentration:

1.0 mg/ml

Description:

Angiopoietins are the ligands of Tie-2 receptor, which is a vascular assembly and maturation-mediating receptor tyrosine kinase that controls blood vessel development. In humans, there are four identified angiopoietins, Ang-1, Ang-2, Ang-3 and Ang-4. They bind the first Ig-like loop plus the EGF-like repeats of Tie-2 whereby they activate Tie-2 and, indirectly, Tie-1 in Tie-1/Tie-2 heterodimers. Angiopoietin-2 is a partial agonist/antagonist of Tie-2 signalling in the endothelium It plays an important role in angiogenesis during the development and growth of human cancers. It also play a part in inflammation-induced vascular remodeling.

Entrez Symbol:

ANGPT2

Uniprot ID:

O15123

Data PDF:

CDM081

Specificity:

Recognizes native and recombinant human Angiopoietin-2.

Host Species:

Mouse

Immunogen:

Recombinant human Angiopoietin-2

Isotype:

IgG1K

Clone:

B-G60

Formulation:

Sterile filtered PBS, carrier and preservative free.

Application:

ELISA

Storage/Stability:

Store in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.