Mouse Anti-Human CD86 (Clone B-S7) mAb, Azide Free mAb

Molecule:

B7-2/CD86

Synonyms:

T-lymphocyte activation antigen CD86, Activation B7-2 antigen, B70, BU63, CTLA-4 counter-receptor B7.2, FUN-1

Species:

Human

Cat. No.:

CDM107A pdf (datasheet)

Quantity/Size:

200 μg

Price:

$390.00 BUY

Concentration:

1 mg/ml

Description:

The mouse monoclonal antibody recognizes human CD86, an immunoglobulin superfamily type I membrane protein expressed by antigen-presenting cells. CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and CTLA-4 (cytotoxic T-lymphocyte-associated protein 4). Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with CTLA-4 negatively regulates T-cell activation and diminishes the immune response.

Entrez Symbol:

CD86

Uniprot Name:

T-lymphocyte activation antigen CD86

Uniprot ID:

P42081

Data PDF:

CDM107

Specificity:

Recognizes CD86, a 80 kDa protein.

Host Species:

Mouse

Immunogen:

B70 transfected P815 cell line

Isotype:

IgG2a kappa light chain

Clone:

B-S7

Formulation:

Sterile-filtered PBS, carrier and preservative free.

Purification:

Ion exchange chromatography

Application:

ELISA

Storage/Stability:

Store at 2-8°C for up to 1 year or in working aliquots at -20°C to -80oC. Avoid repeated freeze-thaw cycles.