Mouse Anti-Human CD117/c-Kit Clone B-K15 Azide Free mAb

Molecule:

KIT

Synonyms:

KIT, PBT, SCFR, C-Kit, CD117

Species:

Human

Cat. No.:

CDM203 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$390.00 BUY

Concentration:

1 mg/ml

Description:

The protein is the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Product: Derived from a hybrid of Myeloma X63/AG.8653 x Balb/c spleen cells.

Entrez Symbol:

KIT

Uniprot Name:

Mast/stem cell growth factor receptor Kit

Uniprot ID:

P10721

Data PDF:

CDM203

Specificity:

Human | Recognizes Stem Cell Factor Receptor, SCF R, c-kit, a 145 kDa protein

Host Species:

Mouse

Immunogen:

Recombinant c-kit

Isotype:

IgG1

Clone:

B-K15

Conjugate:

Unconjugated

Formulation:

Liquid in phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free.

Purification:

Ion exchange chromatography

Application:

FC

Application notes:

Inhibits the Kit-Ligand induced proliferation of TF1 cell line. Recognizes the soluble antigen. Use 10 µl to label 106 cells or 100 µl of whole blood

Storage/Stability:

Stable at +2-8°C for 12 months. For longer storage, freeze aliquots.