Mouse Anti-Human CD154 / CD40L (Clone B-B29) mAb, Azide Free

Molecule:

CD154

Synonyms:

CD40 ligand, Tumor necrosis factor ligand superfamily member 5, TNFSF5, TNF-related activation protein, TRAP, T-cell gp39

Species:

Human

Cat. No.:

CDM183A pdf (datasheet)

Quantity/Size:

200 μg

Price:

$390.00 BUY

Concentration:

1 mg/ml

Description:

CD40 Ligand is expressed on the surface of activated CD4+ T cells, basophils, and mast cells. Binding of CD40L to its receptor, CD40, on the surface of B cells stimulates B-cell proliferation, adhesion and differentiation. A soluble isoform of CD40L has been shown to exist in the circulation. This soluble molecule is a homotrimer of a 18kDa protein exhibiting full activity in B cell proliferation and differentiation assays, is able to rescue B cells from apoptosis and binds soluble CD40. CD40 belongs to the TNF receptor superfamily.

Entrez Symbol:

CD40LG

Uniprot Name:

CD40 ligand

Uniprot ID:

P29965

Data PDF:

CDM183

Specificity:

Recognizes CD40L, TRAP, T-BAM antigen, a 28/30/33 kDa protein

Host Species:

Mouse

Immunogen:

CD40L transfected 3T6 cell line

Isotype:

IgG2a kappa light chain

Clone:

B-B29

Formulation:

Sterile filtered PBS, carrier and preservative free.

Purification:

Ion exchange chromatography

Application:

FC

Storage/Stability:

Store at 2-8°C for up to 1 year or in working aliquots at -20°C to -80oC. Avoid repeated freeze-thaw cycles.