Mouse Anti-Human CD21 / CR2 (Clone B-E5) mAb, Azide Free

Molecule:

CD21/CR2

Synonyms:

Complement receptor type 2, C3d receptor, Epstein-Barr virus receptor, EBV receptor, Complement C3d receptor

Species:

Human

Cat. No.:

CDM162A pdf (datasheet)

Quantity/Size:

200 μg

Price:

$390.00 BUY

Concentration:

200 µg / 200 µl

Description:

Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) is also known as CD21. CR2/CD21 is a membrane protein, which functions as a receptor for Epstein Barr Virus (EBV) binding on B- and T-lymphocytes. Genetic variations in the CR2 gene are associated with susceptibility to Systemic Lupus Erythematosus type 9 (SLEB9).

Entrez Symbol:

CR2

Uniprot Name:

Complement receptor type 2

Uniprot ID:

P20023

Data PDF:

CDM162

Specificity:

Recognizes Epstein-Barr virus receptor (EBV R), CR2, C3d R, a 110 kDa protein

Host Species:

Mouse

Immunogen:

Daudi cell line

Isotype:

IgG2a

Clone:

B-E5

Formulation:

Sterile filtered PBS, carrier and preservative free.

Purification:

Ion exchange chromatography

Application:

FC

Application notes:

Flow cytometry
Induces Human B lymphocyte proliferation.
Competes with EBV for CD21 binding.
Recognizes the soluble antigen.
The Kd is 10 nM.
The optimal concentration should be determined by the user for each specific application.

Storage/Stability:

Stable for 1 year at 2-4°C. For longer storage, aliquot and store at -20°C to -80°C.