Mouse Anti-Human CD28 (Clone B-T3) mAb, Azide Free

Molecule:

CD28

Synonyms:

T-cell-specific surface glycoprotein CD28, Tp44

Species:

Human

Cat. No.:

CDM171A pdf (datasheet)

Quantity/Size:

200 μg

Price:

$390.00 BUY

Concentration:

1 mg/ml

Description:

The mouse monoclonal antibody recognizes human CD28, a cell-surface protein essential for T-cell activation. CD28 provides T cells with a "second signal," or costimulation, which, along with T cell receptor (TCR) ligation, induces proliferation and survival, and cytokine production. TCR stimulation without co-stimulation results in anergy of the T cell, CD28 interacts with CD80 (B7.1) and CD86 (B7.2), found on antigen presenting cells (APCs).

Entrez Symbol:

CD28

Uniprot Name:

T-cell-specific surface glycoprotein CD28

Uniprot ID:

P10747

Data PDF:

CDM171

Specificity:

Recognizes CD28 ( B7/BB1 receptor), a 44 kDa protein.

Host Species:

Mouse

Immunogen:

U266 cell line

Isotype:

IgG2a kappa light chain

Clone:

B-T3

Formulation:

Sterile filtered PBS, carrier and preservative free.

Purification:

Ion exchange Chromatography

Application:

FC, FS , IHC

Application notes:

Inhibits mixed lymphocyte culture, co-stimulates T cell proliferation.

Storage/Stability:

Store at 2-8°C for up to 1 year or in working aliquots at -20°C to -80oC. Avoid repeated freeze-thaw cycles.