Mouse Anti-Human CD45RA (Clone B-C15) PE mAb

Molecule:

CD45RA

Synonyms:

Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, L-CA, T200, CD45

Species:

Human

Cat. No.:

CDM191 pdf (datasheet)

Quantity/Size:

100 tests

Price:

$420.00 BUY

Concentration:

100 tests/ml

Description:

The CD45RA antigen is a member of the CD45 antigen family that also includes the CD45, CD45RB, and CD45RO antigens. The CD45RA antigen is present on approximately 50% of CD4+ T lymphocytes, approximately 75% of CD8+ T lymphocytes, and on essentially all B lymphocytes and natural killer lymphocytes.19. The suppressor inducer T-lymphocyte subset expresses the phenotype CD4+CD45RA+.19. The CD45RA antigen is expressed on naive T lymphocytes; antigen density decreases upon in vitro activation.20 A selective loss of the CD4+CD45RA+ subset during active multiple sclerosis has been demonstrated.

Entrez Symbol:

PTPRC

Uniprot Name:

Receptor-type tyrosine-protein phosphatase C

Uniprot ID:

P08575

Data PDF:

CDM191

Specificity:

Recognizes the restricted Leucocyte Common Antigen (LCA) with different isoforms of 205/220 kDa

Host Species:

Mouse

Immunogen:

Reh 6 cell line

Isotype:

IgG1

Clone:

B-C15

Conjugate:

PE

Formulation:

Lyophilized from a solution in phosphate-buffered saline with 1% BSA and 0.1% sodium azide.

Purification:

Ion exchange chromatography

Reconstitution:

Reconstitute with 1 ml deionized water.

Application:

FC

Application notes:

Flow Cytometry: Use 10 μl to label 1x10E6 cells or 100 μl of whole blood.

Storage/Stability:

Stable at +2-8°C for six months after reconstitution. DO NOT FREEZE.