Mouse Anti-Human CD5 (Clone B-B8) mAb, Azide Free

Molecule:

CD5

Synonyms:

T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1

Species:

Human

Cat. No.:

CDM132A pdf (datasheet)

Quantity/Size:

200 μg

Price:

$390.00 BUY

Concentration:

1 mg/ml

Description:

The mouse monoclonal antibody recognizes human CD5, a glycoprotein expressed on thymocytes, T cells and, at lower levels, on the IgM-secreting B-1 subpopulation of B cells. B-1 cells have limited diversity of their B-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 is upregulated on T cells upon strong activation. In the thymus, there is a correlation with CD5 expression and strength of the interaction of the T cell towards self-peptides. CD5 binds the C-type lectin, CD72, and modulates signaling through the antigen receptors on T and B cells.

Entrez Symbol:

CD5

Uniprot Name:

T-cell surface glycoprotein CD5

Uniprot ID:

P06127

Data PDF:

CDM132

Specificity:

Recognizes CD5, a 67 kDa protein

Host Species:

Mouse

Immunogen:

PHA activated T cells

Isotype:

IgG1 Kappa light chain

Clone:

B-B8

Formulation:

Sterile filtered PBS, carrier and preservative free.

Purification:

Ion exchange Chromatography

Application:

FC, IHC

Application notes:

IHC: recommended dilution 1:50.

Storage/Stability:

Stable at +2-8°C for six months after reconstitution. For longer storage, freeze aliquots.