Mouse Anti-Human CD5 Clone B-B8 PE mAb

Molecule:

CD5

Synonyms:

T1, lymphocyte antigen T1/Leu-1, LEU1, CD5

Species:

Human

Cat. No.:

CDM364 pdf (datasheet)

Quantity/Size:

100 tests

Price:

$420.00 BUY

Description:

The mouse monoclonal antibody recognizes human CD5, a glycoprotein expressed on thymocytes, T cells and, at lower levels, on the IgM-secreting B-1 subpopulation of B cells. B-1 cells have limited diversity of their B-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 is upregulated on T cells upon strong activation. In the thymus, there is a correlation with CD5 expression and strength of the interaction of the T cell towards self-peptides. CD5 binds the C-type lectin, CD72, and modulates signaling through the antigen receptors on T and B cells.

Data PDF:

CDM364

Specificity:

Recognizes Human CD5,a 67 kDa protein

Host Species:

Mouse

Immunogen:

PHA activated T cells

Isotype:

IgG1

Clone:

B-B8

Conjugate:

PE

Formulation:

Phosphate-buffered saline with 1% BSA and 0.1 % sodium azide Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.

Reconstitution:

Reconstitute with 1 ml deionized water

Application:

FC

Application notes:

Use 10 µl to label 106 cells or 100 µl of whole blood

Storage/Stability:

Stable at +2-8°C for six months after reconstitution. DO NOT FREEZE