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The mouse monoclonal antibody recognizes human CD94/ KLRD1, an antigen preferentially expressed on Natural Killer (NK)cells. CD94 is classified as a type II membrane protein because it has an external C terminus. NK cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function.