Mouse Anti-Human CXCR4 (Clone B-R24) mAb, Azide Free

Molecule:

CXCR4

Synonyms:

C-X-C chemokine receptor type 4, CXC-R4, C-X-C chemokine receptor type 4, LESTR, Lipopolysaccharide-associated protein 3, LAP-3, Stromal cell-derived factor 1 receptor, SDF-1

Species:

Human

Cat. No.:

CDM219B pdf (datasheet)

Quantity/Size:

500 μg

Price:

$650.00 BUY

Concentration:

1 mg/ml

Description:

Monoclonal recognizes CXCR4, the receptor for CSCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. CXCR4 acts as a coreceptor (CD4 being the primary receptor) for human immunodeficiency virus-1/HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus.

Entrez Symbol:

CXCR4

Uniprot Name:

C-X-C chemokine receptor type 4

Uniprot ID:

P61073

Data PDF:

CDM219

Specificity:

Recognizes CXCR4, a 39.7 kDa protein

Host Species:

Mouse

Immunogen:

CXCR4 transfected CHO cell line

Isotype:

IgG2a kappa light chain

Clone:

B-R24

Formulation:

Sterile filtered PBS, treated to remove endotoxin. Carrier and preservative free.

Purification:

Ion exchange Chromatography

Application:

FC, FS

Storage/Stability:

Store at 2-8°C for up to 1 year or in working aliquots at -20°C to -80oC. Avoid repeated freeze-thaw cycles.