Mouse Anti-Human Fas / CD95 (Clone B-G27) Azide Free mAb

Molecule:

Fas/CD95

Synonyms:

Tumor necrosis factor receptor superfamily member 6, TNFRSF6, FASLG receptor, Apoptosis-mediating surface antigen FAS, Apo-1 antigen

Species:

Human

Cat. No.:

CDM068A pdf (datasheet)

Quantity/Size:

200 μg

Price:

$390.00 BUY

Concentration:

1 mg/ml

Description:

The monoclonal antibody recognizes human Fas, a member of the TNF-receptor superfamily. This receptor contains a death domain and plays a central role in the physiological regulation of programmed cell death. The interaction of this receptor with its ligand (FasL) allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10 and leads to apoptosis.

Entrez Symbol:

FAS

Uniprot Name:

Tumor necrosis factor receptor superfamily member 6

Uniprot ID:

P25445

Data PDF:

CDM068

Specificity:

Recognizes human CD95, APO-1 antigen, a 45 kDa protein.

Host Species:

Mouse

Immunogen:

Recombinant human Fas

Isotype:

IgG2a kappa light chain

Clone:

B-G27

Formulation:

Sterile filtered PBS, carrier and preservative free.

Purification:

Ion exchange Chromatography

Application:

FC, FS , IHC-F

Application notes:

Triggers apoptotic cell death.

Storage/Stability:

Store at 2-8°C for up to 1 year or in working aliquots at -20°C to -80oC. Avoid repeated freeze-thaw cycles.