Mouse Anti-Human GM-CSF (Clone B-Z13) mAb, Azide Free

Molecule:

GM-CSF

Synonyms:

Granulocyte-macrophage colony-stimulating factor, CSF2, Molgramostin, Sargramostim

Species:

Human

Cat. No.:

CDM329A pdf (datasheet)

Quantity/Size:

200 μg

Price:

$390.00 BUY

Concentration:

1 mg/ml

Description:

The biological effects of GM-CSF are mediated through binding to cell surface receptors, which appear to be widely expressed by hematopoietic cells and also by some non-hematopoietic cells, such as endothelial cells. At least two different functional classes of GM-CSF receptor have been identified. The neutrophil GM-CSF receptor exclusively binds GM-CSF, while interleukin-3 competes for binding of GM-CSF to a second class of receptors detected on some leukemic cell lines. Monitoring of GM-CSF has been found relevant in human prostate cancer, severe mucositis, AIDS, bone marrow transplantation, renal cell carcinoma and prostate cancer, acute lymphoblastic leukemia, pulmonary inflammation, hematological malignancies, infection, lung cancer, Crohn’s disease.

Entrez Symbol:

CSF2

Uniprot Name:

Granulocyte-macrophage colony-stimulating factor

Uniprot ID:

P04141

Data PDF:

CDM329

Specificity:

Recognizes both native and recombinant GM-CSF

Host Species:

Mouse

Immunogen:

Recombinant human GM-CSF

Isotype:

IgG1 Kappa light chain

Clone:

B-Z13

Formulation:

Sterile-filtered PBS, carrier and preservative free.

Purification:

Ion exchange chromatography

Application:

ELISA

Storage/Stability:

Stable at +2-8°C for 12 months. DO NOT FREEZE.