Mouse Anti-Human Granzyme B (Clone GB-10) mAb

Molecule:

Granzyme B

Synonyms:

Cytotoxic T-lymphocyte proteinase 2, Granzyme-2, Cathepsin G-like 1, CTLA-1, C11

Species:

Human

Cat. No.:

CMG110 pdf (datasheet)

Quantity/Size:

0.5 mg

Price:

$950.00 BUY

Description:

This antibody recognizes human Granzyme B, a serine protease most commonly found in the granules of cytotoxic lymphocytes (CTLs) and natural killer (NK) cells. Granzyme B is secreted by these cells along with perforin, the pore forming protein, to mediate apoptosis in target cells.

Uniprot Name:

Granzyme B

Uniprot ID:

P10144

Data PDF:

CMG110

Specificity:

Binds both native and recombinant human Granzyme B in vitro.

Host Species:

Mouse

Isotype:

IgG1

Clone:

GB-10

Formulation:

Prior to lyophilization, sterile filtered PBS containing 125 mM trehalose

Purification:

Ion exchange chromatography.

Reconstitution:

Centrifuge vial briefly before opening. Reconstitute with 0.5 ml sterile distilled water, containing 0.02% sodium azide to prevent bacterial growth (optional).

Application:

ELISA, ELISPOT

Storage/Stability:

Lyophilized product is stable for at least one year at 2-8°C. After reconstitution, the contents can be safely stored at 2-8°C for one month or for one year in working aliquots at -20°C. Avoid repeated freeze-thaw cycles.