Mouse Anti-Human Granzyme B (Clone GB-11) mAb

Molecule:

Granzyme B

Synonyms:

C11, CTLA-1, Cathepsin G-like 1, CTSGL1, CTL proteinase 2, Granzyme-2, Fragmentin-2, Human lymphocyte protein, HLP

Species:

Human

Cat. No.:

CMG111 pdf (datasheet)

Quantity/Size:

500 ug

Price:

$950.00 BUY

Description:

This monoclonal antibody recognizes human Granzyme B, a serine protease most commonly found in the granules of cytotoxic lymphocytes (CTLs) and natural killer (NK) cells. It is secreted by these cells along with the pore forming protein perforin to mediate apoptosis in target cells.

Uniprot Name:

Granzyme B

Uniprot ID:

P10144

Specificity:

Binds native and recombinant human Granzyme B in vitro.

Host Species:

Mouse

Immunogen:

Human Granzyme B derived from NK cell line YT-INDY

Isotype:

IgG1

Clone:

GB-11

Conjugate:

Unconjugated

Formulation:

Lyophilized from sterile filtered 0.5 ml PBS, containing 125 mM trehalose

Purification:

Ion exchange chromatography.

Reconstitution:

Centrifuge vial briefly before opening. Reconstitute with 0.5 ml sterile distilled water, containing 0.02% sodium azide to prevent bacterial growth (optional).

Application:

ELISA, ELISPOT, FC

Storage/Stability:

Store as supplied for 1 year at 2°C to 8°C. Upon reconstitution, prepare working aliquots and store at -20 °C to -80 °C. Avoid repeated freeze-thaw cycles.