Mouse Anti-Human HLA Class II DR (Clone B-C10) mAb, Azide Free

Molecule:

HLA

Synonyms:

HLA class II histocompatibility antigen, DR alpha chain, DR beta chain, MHC class II DRA, MHC class II DRB

Species:

Human

Cat. No.:

CDM346A pdf (datasheet)

Quantity/Size:

200 μg

Price:

$390.00 BUY

Concentration:

1 mg/ml

Description:

HLA class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB1,3,4,5), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa, the beta chain is approximately 26-28 kDa.

Entrez Symbol:

HLA-DRA, HLA-DRB

Uniprot Name:

HLA class II histocompatibility antigen DR

Uniprot ID:

P01903

Data PDF:

CDM346

Specificity:

Recognizes the HLA Class II (DR) membrane

Host Species:

Mouse

Immunogen:

RPMI 8866 and DAUDI cell lines

Isotype:

IgG2b Kappa light chain

Clone:

B-C10

Formulation:

Sterile filtered PBS, carrier and preservative free.

Purification:

Affinity chromatography

Application:

FC

Storage/Stability:

Store at 2-8°C for up to 1 year or in working aliquots at -20°C to -80oC. Avoid repeated freeze-thaw cycles.