Mouse Anti-Human HLA Class II DR (Clone B-C10) mAb

Molecule:

HLA

Synonyms:

HLA class II histocompatibility antigen, DR alpha chain, DR beta chain, MHC class II DRA, MHC class II DRB

Species:

Human

Cat. No.:

CDM347 pdf (datasheet)

Quantity/Size:

200 tests

Price:

$340.00 BUY

Concentration:

100 tests/ml

Description:

HLA class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB1,3,4,5), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa, the beta chain is approximately 26-28 kDa.

Entrez Symbol:

HLA-DRA, HLA-DRB

Uniprot Name:

HLA class II histocompatibility antigen DR

Uniprot ID:

P01903

Data PDF:

CDM347

Specificity:

Recognizes the HLA Class II (DR) membrane

Host Species:

Mouse

Immunogen:

RPMI 8866 and DAUDI cell lines

Isotype:

IgG2b Kappa light chain

Clone:

B-C10

Conjugate:

Unconjugated

Formulation:

PBS containing 1% BSA and 0.1% sodium azide.

Purification:

Ion exchange chromatography

Application:

FC

Application notes:

Flow Cytometry: Use 10 μl to label 10E6 cells or 100 μl of whole blood.

Storage/Stability:

Stable at 2-8°C for 12 months. For longer storage, freeze aliquots.