Mouse Anti-Human IL-1 beta (Clone B-A15) mAb, Azide Free

Molecule:

IL-1 beta

Synonyms:

Interleukin-1 beta, Catabolin

Species:

Human

Cat. No.:

CDM259B pdf (datasheet)

Quantity/Size:

500 μg

Price:

$650.00 BUY

Concentration:

1 mg/ml

Description:

The monoclonal antibody recognizes human IL-1β, a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a pro-protein, which is cleaved to its active form by caspase 1. This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.

Entrez Symbol:

IL1B

Uniprot Name:

Interleukin-1 beta

Uniprot ID:

P01584

Data PDF:

CDM259

Specificity:

Recognizes both native (pro and mature) and recombinant human IL-1 beta

Host Species:

Mouse

Immunogen:

Recombinant human IL-1 beta

Isotype:

IgG1 kappa light chain

Clone:

B-A15

Formulation:

Sterile-filtered PBS, treated to remove endotoxin. Carrier and preservative free

Purification:

Ion exchange chromatography

Application:

ELISA, ELISPOT, FC, FS

Application notes:

Inhibits IL-1 beta induced proliferation on D10S murine cell line. Suitable for intra-cytoplasmic flow cytometry.

Storage/Stability:

Store at 2-8°C for up to 1 year. DO NOT FREEZE.