Mouse Anti-Human IL-1 beta (Clone B-A15) PE mAb

Molecule:

IL-1 beta

Synonyms:

Interleukin-1 beta, Catabolin

Species:

Human

Cat. No.:

CDM260 pdf (datasheet)

Quantity/Size:

100 tests

Price:

$475.00 BUY

Concentration:

100 tests/ml

Description:

The monoclonal antibody recognizes human IL-1β, a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a pro-protein, which is cleaved to its active form by caspase 1. This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Product: Derived from a hybrid of Myeloma X63/AG.8653 x Balb/c spleen cells.

Entrez Symbol:

IL1B

Uniprot Name:

Interleukin-1 beta

Uniprot ID:

P01584

Data PDF:

CDM260

Specificity:

Human | Recognizes both natural (pro and mature) and recombinant human IL-1 beta

Host Species:

Mouse

Immunogen:

Recombinant human IL-1 beta

Isotype:

IgG1 Kappa light chain

Clone:

B-A15

Conjugate:

PE

Formulation:

PBS containing 1 % BSA and 0.1 % sodium azide.

Purification:

Ion exchange chromatography

Reconstitution:

Reconstitute with 1 ml deionized water.

Application:

FC

Application notes:

Suitable for intra-cytoplasmic flow cytometry. Use 10 µl of antibody to label 5x105 cells. Cells require fixation and permeabilization prior to intracellular staining.

Storage/Stability:

Stable at 2-8°C for 12 months. For longer storage, freeze aliquots.