Mouse Anti-Human IL-10 (Clone B-S10) mAb, Azide Free

Molecule:

IL-10

Synonyms:

Interleukin 10, Cytokine synthesis inhibitory factor, CSIF

Species:

Human

Cat. No.:

CDM270B pdf (datasheet)

Quantity/Size:

500 μg

Price:

$650.00 BUY

Concentration:

1.0 mg/ml

Description:

The monoclonal antibody recognizes human IL-10, a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway.

Entrez Symbol:

IL10

Uniprot Name:

Interleukin-10

Uniprot ID:

P22301

Data PDF:

CDM270

Specificity:

Recognizes both native and recombinant human IL-10

Host Species:

Mouse

Immunogen:

Recombinant human IL-10

Isotype:

IgG1 Kappa light chain

Clone:

B-S10

Formulation:

Sterile filtered PBS, carrier and preservative free.

Purification:

Ion exchange chromatography

Application:

ELISA, FS , IHC

Application notes:

Inhibits IL-10 induced proliferation on MC/9 cell line

Storage/Stability:

Store at 2-8°C for up to 1 year or in working aliquots at -20°C to -80oC. Avoid repeated freeze-thaw cycles.