Mouse Anti-Human IL-13 R alpha 1 Azide free Clone B-K19 mAb

Molecule:

IL-13R alpha 1

Synonyms:

NR4, CD213A1, IL-13Ra, IL13RA1, CD213a1 antigen, CT19, IL-13 receptor subunit alpha-1, IL-13R subunit alpha-1, IL-13R-alpha-1, IL-13RA1, IL13 receptor alpha-1 chain, bB128O4.2.1 (interleukin 13 receptor, alpha 1), cancer, testis antigen 19

Species:

Human

Cat. No.:

CDM022 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$390.00 BUY

Concentration:

1 mg/ml

Description:

The monoclonal antibody recognizes human IL13Rα1, a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. Product: Derived from a hybrid of Myeloma X63/AG.8653 x Balb/c spleen cells.

Entrez Symbol:

IL13RA1

Uniprot Name:

Interleukin-13 receptor subunit alpha-1

Uniprot ID:

P78552

Data PDF:

CDM022

Specificity:

Human | Recognizes the IL-13 receptor a1 (IL-13 Ra1).

Host Species:

Mouse

Immunogen:

IL-13Ra1 transfected CHO cell line

Isotype:

IgG1

Clone:

B-K19

Conjugate:

Unconjugated

Formulation:

Sterile filtered (through a 0.22 μm filter) liquid in PBS without preservative and carrier.

Purification:

Ion exchange Chromatography

Application:

IHC

Application notes:

Inhibition of IL-13 activation on monocytes (decreasing of IL-6 production).

Storage/Stability:

Antibody solution is stable at 2-8°C for 1 year. Aliquot and freeze for longer storage.