Mouse Anti-Human IL-15 (Clone B-E29) mAb, Azide Free

Molecule:

IL-15

Synonyms:

Interleukin-15

Species:

Human

Cat. No.:

CDM282B pdf (datasheet)

Quantity/Size:

500 µg

Price:

$650.00 BUY

Concentration:

1 mg/ml

Description:

The monoclonal antibody recognizes human Interleukin-15 (IL-15), a cytokine that regulates T and natural killer cell activation and proliferation. IL-15 and IL-2 share many biological activities; both bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2. Studies of the mouse counterpart suggested that IL-15 may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.

Entrez Symbol:

IL15

Uniprot Name:

Interleukin-15

Uniprot ID:

P40933

Data PDF:

CDM282

Specificity:

Native and Recombinant Human IL-15

Host Species:

Mouse

Immunogen:

Recombinant Human IL-15

Isotype:

IgG1 Kappa light chain

Clone:

B-E29

Formulation:

Sterile filtered PBS, treated to remove endotoxins. Carrier and preservative free.

Purification:

Ion-exchange chromatography

Application:

ELISA, FC, FS

Application notes:

Inhibits IL-15 induced proliferation on Kit 225 cell line.

Storage/Stability:

Store at 2-8°C for up to 1 year or in working aliquots at -20°C to -80oC. Avoid repeated freeze-thaw cycles.