Mouse Anti-Human IL-17F Clone B-F60 Azide Free mAb

Molecule:

IL-17F

Synonyms:

ML1, ML-1, CANDF6, interleukin-17F

Species:

Human

Cat. No.:

CDM288 pdf (datasheet)

Quantity/Size:

500 μg

Price:

$595.00 BUY

Concentration:

1 mg / mL

Description:

The monoclonal antibody recognizes human IL-17F, a member of the IL-17 cytokine family produced by activated T-cells and monocytes. IL-17F is considered an inflammatory cytokine since it induces many proinflammatory cytokines and chemokines, including IL6, IL8, and CSF2/GM-CSF. It also inhibits the angiogenesis of endothelial cells and induces endothelial cells to produce IL2, TGFB1, and MCP-1. IL-17F shares strongest homology to IL-17A. An IL-17A/F biologically active heterodimer was found to be expressed in Th17 cells, together with both IL-17A and IL-17F homodimers.

Entrez Symbol:

IL17F

Uniprot Name:

Interleukin-17F

Uniprot ID:

Q96PD4

Data PDF:

CDM288

Specificity:

Recognizes recombinant and native human IL-17F

Host Species:

Mouse

Immunogen:

Recombinant human IL-17F

Isotype:

IgG2b

Clone:

B-F60

Conjugate:

Unconjugated

Formulation:

Liquid in phosphate buffered saline, sterile filtered. Carrier and preservative free.

Purification:

Ion exchange chromatography

Application:

FS , Neutralizing

Application notes:

The optimal concentration should be determined by the user for each specific application.

Storage/Stability:

Stable at 2-8 °C for one year. For longer storage, freeze in working aliquots and store at -20 °C to -80°C.