Mouse Anti-Human IL-17F (Clone B-G46) mAb, Azide Free

Molecule:

IL-17F

Synonyms:

Interleukin-17F, ML-1

Species:

Human

Cat. No.:

CDM123B pdf (datasheet)

Quantity/Size:

500 μg

Price:

$650.00 BUY

Concentration:

1.0 mg/mL

Description:

IL-17F is a member of the IL-17 cytokine family produced by activated CD4+ T-cells and monocytes. IL-17F is considered an inflammatory cytokine since it induces many proinflammatory cytokines and chemokines. IL-17F shares strongest homology to IL-17A (sharing about 50% amino acid). An IL-17A/F biologically active heterodimer was found to be expressed in Th17 cells together with IL-17A and IL-17F homodimers. IL-17F stimulated the production of several other cytokines, including IL6, IL8, and GM-CSF. It also inhibits the angiogenesis of endothelial cells and induces endothelial cells to produce IL2, TGFB1, and MCP-1.

Entrez Symbol:

IL17F

Uniprot Name:

Interleukin-17F

Uniprot ID:

Q96PD4

Data PDF:

CDM123

Specificity:

Recognizes both recombinant and native human IL-17F

Host Species:

Mouse

Immunogen:

Recombinant human IL-17F

Isotype:

IgG2b Kappa light chain

Clone:

B-G46

Formulation:

Sterile filtered PBS, carrier and preservative free.

Purification:

Ion exchange chromatography

Application:

ELISA, ELISPOT

Application notes:

This mAb can be used as a capture antibody in a human IL-17F sandwich Immunoassay to detect human IL-17F in combination with biotinylated human IL-17F (Clone B-F60) biotinylated detection antibody (CDM450). Suggested concentration range: 1-5 µg/mL, however the optimal concentration should be determined by the user.

Storage/Stability:

Store at 2-8°C for up to 1 year or in working aliquots at -20°C to -80oC. Avoid repeated freeze-thaw cycles.