Mouse Anti-Human IL-2R subunit alpha / CD25 (Clone B-G3) Azide Free mAb

Molecule:

IL-2R alpha

Synonyms:

Interleukin-2 receptor subunit alpha, IL-2 RA, p55; TAC antigen

Species:

Human

Cat. No.:

CDM005 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$390.00 BUY

Concentration:

1 mg/ml

Description:

This antibody can be used as a Capture Antibody in a human IL-2RA sandwich Immunoassay to detect humanIL-2RA in combination with biotinylated human IL-2RA Detection Antibody (Cat No CDM418). 

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.

Entrez Symbol:

IL2RA

Uniprot Name:

Interleukin-2 receptor subunit alpha

Uniprot ID:

P01589

Data PDF:

CDM005

Specificity:

Human Interleukin 2 Receptor alpha chain (IL-2Rα), a 55 kDa protein. Recognizes both soluble and membrane-bound human IL-2Rα.

Host Species:

Mouse

Immunogen:

PHA activated T cells

Isotype:

IgG1

Clone:

B-G3

Conjugate:

Unconjugated

Formulation:

Sterile filtered PBS without preservative and carrier.

Purification:

Ion exchange Chromatography

Application:

ELISA, FC

Application notes:

No effect on Mixed Lymphocyte Culture
ELISA: 0.5-2.5 µg/ml

Storage/Stability:

Antibody solution is stable at 2-4°C for 1 year. Aliquot and freeze for longer storage.