Mouse Anti-Human IL-27 (Clone B-G49) mAb, Azide Free

Molecule:

IL-27

Synonyms:

Interleukin-27 subunit alpha (p28) and Interleukin-27 subunit alpha (EBV-induced gene 3 protein)

Species:

Human

Cat. No.:

CDM283B pdf (datasheet)

Quantity/Size:

500 μg

Price:

$650.00 BUY

Concentration:

1 mg/ml

Description:

Interleukin 27 is heterodimeric cytokine belonging to the IL-12 family that is composed of two subunits,Epstein-Barr virus-induced gene 3 (EBI3), a 33-kDa glycosylated protein, and IL-27p28, a 28-kDa peptide. IL-27 is an early product of activated antigen-presenting cells and drives rapid clonal expansion of naïve but not memory CD4+ T cells. The effects of IL-27 are eliciting by its interaction with a specific cell surface receptor complex composed of two proteins known as WSX-1 (TCCR) and gp130. IL-27 has both pro- and anti-inflammatory properties.

Entrez Symbol:

IL27A, EBI3

Uniprot Name:

Interleukin-27 subunit alpha

Uniprot ID:

Q8NEV9, Q14213

Data PDF:

CDM283

Specificity:

Recognizes both native and recombinant human IL-27

Host Species:

Mouse

Immunogen:

Recombinant human IL-27

Isotype:

IgG2a kappa light chain

Clone:

B-G49

Formulation:

Sterile-filtered PBS, carrier and preservative free.

Purification:

Ion exchange Chromatography

Application:

ELISA, FC

Application notes:

Suitable for flow cytometry on dendritic cells.

Storage/Stability:

Store at 2-8°C for up to 1 year or in working aliquots at -20°C to -80oC. Avoid repeated freeze-thaw cycles.