Human Anti-SARS-CoV-2 Nucleoprotein (Clone CR3018) mAb, Azide Free

Synonyms:

Nucleoprotein, Nucleocapsid protein, NC, Protein N

Species:

SARS-CoV-2

Cat. No.:

CDH002B pdf (datasheet)

Quantity/Size:

500 ug

Price:

$990.00 BUY

Concentration:

1.0 mg/ml

Description:

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). The structural proteins of SARS-CoV-2 include the envelope protein (E), spike or surface glycoprotein (S), membrane protein (M) and the nucleocapsid protein (N). The nucleocapsid phosphoprotein is a structural protein that binds to, protects the viral RNA genome and is involved in packaging the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. May modulate transforming growth factor-beta signaling by binding to the transcriptional modulator of the host, smad3. The N protein has been suggested as an antiviral drug target.

Entrez Symbol:

N

Uniprot Name:

Nucleoprotein

Uniprot ID:

P0DTC9

Data PDF:

CDH002

Specificity:

Nucleoprotein of SARS-CoV-2 (aa 11-19) which corresponds to the sequence RSAPRITFG of the N protein of SARS-CoV

Host Species:

Human

Immunogen:

Generated by sequencing peripheral blood lymphocytes of a patient exposed to the SARS-CoV.

Isotype:

IgG1 kappa light chain

Clone:

CR3018

Formulation:

Sterile-filtered PBS. Carrier and preservative free.

Application:

ELISA

Storage/Stability:

Store at 2-8°C.