Mouse Anti-Human Interleukin-4 (Clone 5B5) mAb

Molecule:

IL-4

Synonyms:

B-cell stimulatory factor, BSF-1, IL-4, Lymphocyte stimulatory factor 1

Species:

Human

Cat. No.:

CMI020 pdf (datasheet)

Quantity/Size:

0.5 mg

Price:

$690.00 BUY

Description:

The mouse monoclonal antibody recognizes human interleukin-4 (IL-4), a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for the IL-4 receptor. IL -4 has many functions, including stimulation of T cell and B cell proliferation, induction of differentiation of naive CD4+ T cells into Th2 cells, and induction of B cell isotype switching to IgE, associated with an allergic phenotype.

Entrez Symbol:

IL4

Uniprot Name:

Interleukin-4

Uniprot ID:

P05112

Data PDF:

CMI020

Specificity:

Binds with high efficiency to native and recombinant human IL-4.
Efficiently inhibits IL-4-induced IgE production and IL-4-induced T cell proliferation.

Host Species:

Mouse

Isotype:

IgG1

Clone:

5B5

Formulation:

Lyophilized from sterile filtered PBS containing 125 mM trehalose.

Reconstitution:

Centrifuge vial briefly before opening. Reconstitute with 0.5 ml sterile distilled water, containing 0.02% sodium azide to prevent bacterial growth (recommended). Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.

Application:

ELISA, ELISPOT, FS , IHC

Application notes:

ELISA, ELISPOT: capture antibody

Functional Studies: in vitro neutralization

IHC

Storage/Stability:

Store at 2-8°C