Mouse Anti-Human IL-4 (Clone B-G28) PE mAb

Molecule:

IL-4

Synonyms:

Interleukin-4, B cell stimulatory factor, BSF-1, Lymphocyte stimulatory factor

Species:

Human

Cat. No.:

CDM280 pdf (datasheet)

Quantity/Size:

100 μg

Price:

$475.00 BUY

Concentration:

100

Description:

IL-4 is a lymphokine that co-stimulates the proliferation of activated B- and T-cells, augments the cytotoxic activity of lymphocytes and monocytes and enhances the functional activity of myeloid cells. Produced by mast cells, T-cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ cells into helper Th2 cells characterized by their cytokine secretion-profile that includes secretion of IL-4, IL-5, IL-6, IL-10 and IL-13 which favour a humoral immune response. In addition, IL-4 can inhibit the proliferation of TNF, IL-1 and IL-6 by macrophages.

Entrez Symbol:

IL4

Uniprot Name:

Interleukin-4

Uniprot ID:

P05112

Data PDF:

CDM280

Specificity:

Recognizes both native and recombinant human IL-4

Host Species:

Mouse

Immunogen:

Recombinant human IL-4

Isotype:

IgG1

Clone:

B-G28

Conjugate:

PE

Formulation:

Lyophilized from PBS containing 1% BSA and 0.1% sodium azide.

Purification:

Ion exchange chromatography

Reconstitution:

Reconstitute with 1 ml deionized water.

Application:

ELISA, FC

Application notes:

Suitable for intra-cytoplasmic flow cytometry. Use 10 ┬Ál of antibody to label 5x105 cells. Cells require fixation and permeabilization prior to intracellular staining.

Storage/Stability:

Store at 2-8°C for six months after reconstitution. DO NOT FREEZE.