Mouse Anti-Human IL-6 (Clone B-E8) mAb, Azide Free

Molecule:

IL-6

Synonyms:

Interleukin-6, B-cell stimulatory factor 2, BSF-2, CTL differentiation factor, CDF, Hybridoma growth factor, Interferon beta-2, IFN-beta-2

Species:

Human

Cat. No.:

CDM265B pdf (datasheet)

Quantity/Size:

500 μg

Price:

$650.00 BUY

Concentration:

1 mg/ml

Description:

The monoclonal antibody recognizes IL-6, a cytokine that functions in inflammation and the maturation of B cells. In addition, IL-6 has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha.

Entrez Symbol:

IL6

Uniprot Name:

Interleukin-6

Uniprot ID:

P05231

Data PDF:

CDM265

Specificity:

Recognizes both native and recombinant human IL-6

Host Species:

Mouse

Immunogen:

Recombinant human IL-6

Isotype:

IgG1 Kappa light chain

Clone:

B-E8

Formulation:

Sterile-filtered PBS, carrier and preservative free.

Purification:

Ion exchange chromatography

Application:

ELISA, ELISPOT, FC, FS

Application notes:

ELISA: Use as Capture Antibody at 0.5-2.5 µg/ml in a human IL-6 sandwich ELISA in combination with biotinylated human IL-6 Detection Antibody (Cat No CDM426).

ELISPOT: Use as Capture Antibody at 5-10 µg/ml

The optimal concentration should be determined by the user for each specific application.

Storage/Stability:

Store at 2-8°C for up to 1 year or in working aliquots at -20°C to -80oC. Avoid repeated freeze-thaw cycles.