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Mouse Anti-Human IL-6 Clone B-E4 Biotin Detection mAb

Molecule:

IL-6

Synonyms:

HGF, HSF, BSF2, IL-6, IFNB2

Species:

Human

Cat. No.:

CDM426 pdf (datasheet)

Quantity/Size:

100 μg

Price:

$650.00 BUY

Concentration:

0.1 mg/ml

Description:

Mouse Anti-Human IL-6 Clone B-E4 Biotin Detection mAb.

IL-6 is a cytokine that functions in inflammation and the maturation of B cells. In addition, it has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The malfunction of IL-6 has been associated with a wide range of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.

Entrez Symbol:

IL6

Uniprot Name:

Interleukin-6

Uniprot ID:

P05231

Data PDF:

CDM426

Specificity:

Recognizes both natural and recombinant IL-6

Host Species:

Mouse

Immunogen:

Recombinant human IL-6

Isotype:

IgG2b

Clone:

B-E4

Conjugate:

Biotin

Formulation:

Liquid in PBS with 1% BSA and 0.09% Sodium Azide. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.

Purification:

Ion exchange chromatography

Application:

ELISA, ELISPOT

Application notes:

Detection Antibody: ELISA / ELISPOT: 0.05-0.5 µg/ml
ELISA Detection Antibody. This Antibody can be used as Detection Ab in a human IL-6 sandwich immunoassay to detect human IL-6 in combination with human IL-6 Capture Antibody (Cat No. CDM402). The suggested coating concentration range below should be optimized by each laboratory for each application.

Storage/Stability:

Store at 2-4°C. For longer storage, aliquot and freeze at -20°C. Avoid repeated freezethaw cycles.