Mouse Anti-Human Insulin Receptor, alpha chain (Clone 83-7) mAb

Molecule:

INSR

Synonyms:

IR, CD220, INSR

Species:

Human

Cat. No.:

MAG1 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$380.00 BUY

Description:

Human insulin receptor antibody, clone 83-7, is a murine monoclonal antibody that recognizes an epitope within amino acids 140-301 (the cysteine rich region) of the extracellular domain (alpha chain) of the human insulin receptor. The antibody enhances the binding of insulin to the insulin receptor of 3T3 cells and stimulates insulin-mediated thymidine incorporation in these cells.

Entrez Symbol:

INSR

Uniprot Name:

Insulin receptor

Uniprot ID:

P06213

Data PDF:

MAG1

Specificity:

Recognizes an epitope located within amino acids 140-301 (the cysteine rich region) of the extracellular domain alpha-chain of the human insulin receptor.

Host Species:

Mouse

Immunogen:

IM9 lymphocyte preparation

Isotype:

IgG1

Clone:

83-7

Formulation:

Lyophilized

Purification:

Protein A affinity chromatography from conditioned medium

Reconstitution:

Centrifuge vial prior to opening. Reconstitute with 200 µL PBS, pH 7.4.

Application:

ELISA, IP , WB

Application notes:

Immunoprecipitation: 1:5000 dilution
Western Blot: 1:5000 dilution
ELISA: 1:5000 dilution
The optimal concentration should be determined by the user for each specific application.

Storage/Stability:

Store as supplied at 2-8°C for up to 2 years. Store reconstituted in working aliquots at -20°C to -80°C. Avoid repeated freeze-thaw cycles.