Mouse Anti-Human Integrin alpha L / CD11a (Clone B-B15) mAb, Azide Free

Molecule:

ITGAL/CD11A

Synonyms:

CD11A, Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, Leukocyte function-associated molecule 1 alpha chain

Species:

Human

Cat. No.:

CDM027B pdf (datasheet)

Quantity/Size:

500 μg

Price:

$650.00 BUY

Concentration:

1 mg/ml

Description:

The mouse monoclonal antibody recognizes human Integrin alpha L/CD11a. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This integrin alpha L/CD11a chain and the integrin beta 2 beta chain (ITGB2) combine to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, intercellular adhesion molecules (ICAMs) 1-3, and also functions in lymphocyte co-stimulatory signaling. Product: Derived from a hybrid of Myeloma X63/AG.8653 x Balb/c spleen cells.

Entrez Symbol:

ITGAL

Uniprot Name:

Integrin alpha-L

Uniprot ID:

P20701

Data PDF:

CDM027

Specificity:

Recognizes an L integrin of LFA-1 complex, a 180 kDa protein

Host Species:

Mouse

Immunogen:

Human PBL

Isotype:

IgG1

Clone:

B-B15

Formulation:

Sterile filtered PBS, carrier and preservative free.

Purification:

Ion exchange Chromatography

Application:

FC

Storage/Stability:

Antibody solution is stable at 2-8°C for 1 year. Aliquot and freeze for longer storage.