Mouse Anti-Human LBP (Clone biG 43) mAb

Molecule:

LBP

Synonyms:

Lipopolysaccharide Binding Protein, LPS-binding protein, BPI fold containing family D, member 2, BPIFD2

Species:

Human

Cat. No.:

CML007 pdf (datasheet)

Quantity/Size:

100 µg

Price:

$415.00 BUY

Concentration:

1 mg/ml, prior to lyophilization

Description:

LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).

Entrez Symbol:

LBP

Data PDF:

CML007

Specificity:

Human LBP

Host Species:

Mouse

Immunogen:

Recombinant Human LBP

Isotype:

IgG1

Clone:

biG 43

Formulation:

Lyophilized in PBS without preservatives or additives

Purification:

Protein G affinity chromatography

Reconstitution:

.

Cross Reactivity:

1057

Application:

ELISA, WB

Application notes:

Human ELISA: recommended dilution of 1:150,000.
Bovine ELISA: recommended dilution of 1:10 to 1:400.
No inhibition of LPS binding to membrane bound CD14.
The optimal concentration should be determined by the user for each specific application.

Storage/Stability:

Store in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.