Mouse Anti-Human LBP (Clone biG 43) mAb

Molecule:

LBP

Synonyms:

Lipopolysaccharide Binding Protein, LPS-binding protein, BPI fold containing family D, member 2, BPIFD2

Species:

Human

Cat. No.:

CML007 pdf (datasheet)

Quantity/Size:

100 µg

Price:

$415.00 BUY

Concentration:

1 mg/ml, prior to lyophilization

Description:

LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).

Entrez Symbol:

LBP

Data PDF:

CML007

Specificity:

Human LBP

Host Species:

Mouse

Immunogen:

Recombinant Human LBP

Isotype:

IgG1

Clone:

biG 43

Formulation:

Lyophilized in PBS without preservatives or additives

Purification:

Protein G affinity chromatography

Reconstitution:

Centrifuge vial prior to opening. Reconstitute with sterile ultra-pure deionized water. This product can be diluted further with PBS or other buffers.

Cross Reactivity:

1057

Application:

ELISA, WB

Application notes:

Human LBP ELISA: recommended dilution of 1:100,000.
Bovine LBP ELISA: recommended dilution of 1:10 (good) - 1:400 (detectable).
Western Blot

The optimal concentration should be determined by the user for each specific application.

Storage/Stability:

Upon receipt, store as supplied at -20°C to -80°C for up to 1 year. Reconstituted product should be used immediately or stored in working aliquots at -20°C to -80°C. For long term storage, it is recommended to add a carrier protein (0.1% BSA). Avoid repeated freeze-thaw cycles.