LBP

Lipopolysaccharide Binding Protein, LPS-binding protein, BPI fold containing family D, member 2, BPIFD2

Human

CML007 pdf (datasheet)

100 µg

$415.00 BUY

1 mg/ml, prior to lyophilization

LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).

LBP

CML007

Human LBP

Mouse

Recombinant Human LBP

IgG1

biG 43

Lyophilized in PBS without preservatives or additives

Protein G affinity chromatography

Centrifuge vial prior to opening. Reconstitute with sterile ultra-pure deionized water. This product can be diluted further with PBS or other buffers.

1057

ELISA, WB

Human LBP ELISA: recommended dilution of 1:100,000.
Bovine LBP ELISA: recommended dilution of 1:10 (good) - 1:400 (detectable).
Western Blot

The optimal concentration should be determined by the user for each specific application.

Upon receipt, store as supplied at -20°C to -80°C for up to 1 year. Reconstituted product should be used immediately or stored in working aliquots at -20°C to -80°C. For long term storage, it is recommended to add a carrier protein (0.1% BSA). Avoid repeated freeze-thaw cycles.