LBP

Lipopolysaccharide Binding Protein, LPS-binding protein, BPI fold containing family D, member 2, BPIFD2

Human

CML007 pdf (datasheet)

100 µg

$415.00 BUY

1 mg/ml, prior to lyophilization

LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).

LBP

CML007

Human LBP

Mouse

Recombinant Human LBP

IgG1

biG 43

Lyophilized in PBS without preservatives or additives

Protein G affinity chromatography

.

1057

ELISA, WB

Human ELISA: recommended dilution of 1:150,000.
Bovine ELISA: recommended dilution of 1:10 to 1:400.
No inhibition of LPS binding to membrane bound CD14.
The optimal concentration should be determined by the user for each specific application.

Store in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.