Mouse Anti-Human Perforin-1 (Clone B-D48) mAb, Azide Free

Molecule:

PRF1

Synonyms:

P1, Cytolysin, Lymphocyte pore-forming protein, PFP

Species:

Human

Cat. No.:

CDM245A pdf (datasheet)

Quantity/Size:

200 μg

Price:

$390.00 BUY

Concentration:

1 mg/ml

Description:

Perforin 1 has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood.

Entrez Symbol:

PRF1

Uniprot Name:

Perforin-1

Uniprot ID:

P14222

Data PDF:

CDM245

Specificity:

Recognizes human Perforin, a 70 kDa protein

Host Species:

Mouse

Immunogen:

Native human Perforin

Isotype:

IgG1 Kappa light chain

Clone:

B-D48

Formulation:

Sterile-filtered PBS, carrier and preservative free.

Purification:

Ion exchange Chromatography

Application:

ELISA, FC, IHC-F, WB

Storage/Stability:

Store at 2-8°C for up to 1 year or in working aliquots at -20°C to -80°C. Avoid repeated freeze-thaw cycles.