Perforin

P1, Cytolysin, Lymphocyte pore-forming protein, PFP

Human

CDM090A pdf (datasheet)

200 μg

$390.00 BUY

1 mg/ml

Perforin 1 has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood.

PRF1

Perforin-1

P14222

CDM090

Recognizes human Perforin, a 70 kDa protein

Mouse

Native human perforin

IgG2b Kappa light chain

B-E48

Sterile-filtered PBS, carrier and preservative free.

Ion exchange chromatography

ELISA, ELISPOT

ELISA: Use as a Capture Antibody at 0.5-2.5 µg/ml in a human Perforin sandwich ELISA in combination with biotinylated human Perforin Detection Antibody (Cat No CDM438).

Optimal coating concentration should be determined by the user.

Stable at +2-8°C for 12 months. DO NOT FREEZE.