Mouse Anti-Human Tissue Factor Pathway Inhibitor Clone CLB/TFPI Kunitz-3 mAb

Molecule:

TFPI

Synonyms:

EPI , LACI , TFI1 , TFPI

Species:

Human

Cat. No.:

CS-MW1847 pdf (datasheet)

Quantity/Size:

1 mg

Concentration:

2.0 mg/ml

Description:

Mouse monoclonal antibody to Human Tissue Factor Pathway Inhibitor (TFPI). TFPI is a protease inhibitor with three tandem Kunitz-type inhibitor domains that inhibits the tissue factor (TF)-initiated blood coagulation cascade reactions by forming a complex with factor VIIa/TF via the first Kunitz-type inhibitor domain and with factor Xa via the second Kunitz-type inhibitor domain. The third Kunitz-type inhibitor domain of TFPI has no ability to inhibit protease but plays an important role in the functions of TFPI.

Entrez Symbol:

TFPI

Uniprot ID:

P10646

Data PDF:

CS-MW1847

Specificity:

Anti-Kunitz domain 3 (aa 160 - 250)

Host Species:

Mouse

Isotype:

IgG1

Clone:

CLB/TFPI Kunitz-3

Formulation:

20 mM TRIS and 150 mM NaCl, pH 8.0

Purification:

Purified by Protein A affinity chromatography.

Application:

ELISA, FC, Neutralizing , WB

Application notes:

Useful as tracer antibody in human TFPI ELISA in conjunction with coating antibody TFPI (Kunitz-2) (CS-MW1845) for tests in plasma and serum. This combination measures full-length TFPI. This antibody is also useful for western blot analysis and in FACS analysis for detection of TFPI on endothelial and smooth muscle cells

Storage/Stability:

Store in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.