Mouse Anti-Human TNF-alpha (Clone B-C7) mAb, Azide Free

Molecule:

TNF-alpha

Synonyms:

Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2

Species:

Human

Cat. No.:

CDM276B pdf (datasheet)

Quantity/Size:

500 μg

Price:

$650.00 BUY

Concentration:

1.0 mg/ml

Description:

The monoclonal antibody recognizes TNF-α, a multifunctional proinflammatory cytokine that belongs to the TNF superfamily and is mainly secreted by macrophages. TNF-α can bind to and functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/ TNFBR. It is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation.

Entrez Symbol:

TNF

Uniprot Name:

Tumor necrosis factor

Uniprot ID:

P01375

Data PDF:

CDM276

Specificity:

Recognizes both native and recombinant human TNF-α

Host Species:

Mouse

Immunogen:

Recombinant human TNF-α

Isotype:

IgG1 kappa light chain

Clone:

B-C7

Formulation:

Sterile filtered PBS, treated to remove endotoxins. Carrier and preservative free.

Purification:

Ion exchange chromatography

Application:

ELISA, ELISPOT, FS , IHC

Application notes:

Inhibits TNF-alpha induced cytotoxicity on U937 cells. Recognizes TNF-α bound on its receptor.

Storage/Stability:

Stable at 2-8°C for up to 12 months. DO NOT FREEZE.