Mouse Anti-Human TNF-alpha (Clone B-F7) Azide Free mAb

Molecule:

TNF-alpha

Synonyms:

Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2

Species:

Human

Cat. No.:

CDM287B pdf (datasheet)

Quantity/Size:

500 μg

Price:

$650.00 BUY

Concentration:

1 mg/ml

Description:

The monoclonal antibody recognizes TNF-α, a multifunctional proinflammatory cytokine that belongs to the TNF superfamily and is mainly secreted by macrophages. TNF-α can bind to and functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/ TNFBR. It is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation.

Entrez Symbol:

TNF

Uniprot Name:

Tumor necrosis factor

Uniprot ID:

P01375

Data PDF:

CDM287

Specificity:

Recognizes both native and recombinant human TNF-alpha

Host Species:

Mouse

Immunogen:

Recombinant human TNF-alpha

Isotype:

IgG1 Kappa light chain

Clone:

B-F7

Formulation:

Sterile-filtered PBS, carrier and preservative free.

Purification:

Affinity chromatography & Ion exchange chromatography

Application:

ELISA, ELISPOT

Application notes:

ELISA: Use as a Capture Antibody at 1 - 10 µg/ml in a human TNF-alpha sandwich ELISA in combination with biotinylated human TNF-alpha Detection Antibody (Cat No CDM436).

Storage/Stability:

Store at 2-8°C for up to 1 year or in working aliquots at -20°C to -80oC. Avoid repeated freeze-thaw cycles.