Mouse Anti-Human TNF-alpha Clone T3 mAb

Synonyms:

Tumor necrosis factor, Cachetin, TNF-a

Species:

Human

Cat. No.:

MON9067 pdf (datasheet)

Quantity/Size:

100 μg

Price:

$1,095.00 BUY

Concentration:

0.1 mg/ml

Description:

Tumor Necrosis Factor alpha (TNF-α) is a cytokine which has various immunomodulatory, antitumor and cytotoxic effects. TNF-α has been detected in various inflammatory status and appears to be a critical mediator in the lethality of septic shock. Furthermore, TNF-α has also been found in inflammatory foci such as synovial effusions in rheumatoid arthritis, systemic circulation in septic shock, parasitemia and rejection of renal transplants.

Uniprot Name:

Tumor necrosis factor

Uniprot ID:

P01375

Data PDF:

MON9067

Specificity:

Reacts with free soluble (17 kDa) and membrane (26 kDa) human TNF-α.

Host Species:

Mouse

Immunogen:

Recombinant human TNF-α

Isotype:

IgG1

Clone:

T3

Formulation:

Sterile-filtered PBS, containing 0.02% sodium azide and 0.1% bovine serum albumin.

Application:

FC, FS , IA, IB, IP , WB

Application notes:

The antibody inhibits the biological activity of soluble and membrane TNF-α. The antibody can be a useful tool to discriminate between receptor bound soluble (17 kDa) and the membrane (26 kDa) form of TNF-α. For this purpose we recommend to use this antibody in combination with catalog no. MON9068: anti-TNF-α antibody , which recognizes only soluble and membrane TNF-α, but not the receptor bound TNF-α.

Storage/Stability:

Store at 2-8°C for up to one year.