Mouse Anti-Human TRAILR2 / CD262 (Clone B-D37) Azide free mAb

Molecule:

TRAILR2/DR5

Synonyms:

Tumor necrosis factor receptor superfamily, member 10b, TRAIL-R2, Death receptor

Species:

Human

Cat. No.:

CDM237 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$390.00 BUY

Concentration:

1 mg/ml

Description:

The monoclonal antibody recognizes the human protein TRAILR2/DR5, a member of the TNF-receptor superfamily. The receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal.

Entrez Symbol:

TNFRSF10B

Uniprot Name:

Tumor necrosis factor receptor superfamily member 10B

Uniprot ID:

O14763

Data PDF:

CDM237

Specificity:

Recognizes TRAILR2, a 42-46 kDa protein

Host Species:

Mouse

Immunogen:

Recombinant human TRAIL R2/Fc chimera

Isotype:

IgG2b

Clone:

B-D37

Conjugate:

Unconjugated

Formulation:

Sterile-filtered PBS. Carrier and preservative free.

Purification:

Ion exchange Chromatography

Application:

ELISA, FC, FS , IP

Application notes:

Agonist: induced apoptosis on Jurkat cells. Enhances TRAIL induced apoptosis of U937 cell line.

Storage/Stability:

Stable at +2-8°C for 12 months. For longer storage, freeze aliquots.