Mouse Anti-Human TRAILR1 / CD261 (Clone B-N36) mAb, Azide Free

Molecule:

TRAILR1/DR4

Synonyms:

Tumor necrosis factor receptor superfamily, member 10A, Death receptor 4, CD261, TNF-related apoptosis-inducing ligand receptor 1, TRAIL-R1

Species:

Human

Cat. No.:

CDM231A pdf (datasheet)

Quantity/Size:

200 μg

Price:

$390.00 BUY

Concentration:

1 mg/ml

Description:

The monoclonal antibody recognizes human TRAILR-1, a surface protein which, when engaged by its ligand TRAIL, transduces a cell death signal and induces apoptosis.

Entrez Symbol:

TNFRSF10A

Uniprot Name:

Tumor necrosis factor receptor superfamily member 10A

Uniprot ID:

O00220

Data PDF:

CDM231

Specificity:

Recognizes TRAIL-R1, a 43-46 kDa protein

Host Species:

Mouse

Immunogen:

Recombinant human TRAIL R1/Fc chimera

Isotype:

IgG1 Kappa light chain

Clone:

B-N36

Formulation:

Sterile filtered PBS, treated to remove endotoxins. Carrier and preservative free.

Purification:

Ion exchange Chromatography

Application:

ELISA, FC, FS , Neutralizing

Application notes:

Neutralizes TRAIL induced apoptosis on HEL cell line

Storage/Stability:

Store at 2-8°C for up to 1 year or in working aliquots at -20°C to -80oC. Avoid repeated freeze-thaw cycles.