Mouse Anti-Human TRAILR1 / CD261 (Clone B-N36) mAb

Molecule:

TRAILR1/DR4

Synonyms:

APO2; DR4; Tumor necrosis factor receptor superfamily, member 10a

Species:

Human

Cat. No.:

CDM233 pdf (datasheet)

Quantity/Size:

200 tests

Price:

$340.00 BUY

Concentration:

100 tests/ml

Description:

The monoclonal antibody recognizes human TRAILR-1, a surface protein which, when engaged by its ligand TRAIL, transduces a cell death signal and induces apoptosis.

Entrez Symbol:

TNFRSF10A

Uniprot Name:

Tumor necrosis factor receptor superfamily member 10A

Uniprot ID:

O00220

Data PDF:

CDM233

Specificity:

Human TRAILR1/DR4, a 43-46 kDa protein

Host Species:

Mouse

Immunogen:

Recombinant human TRAIL R1/Fc chimera

Isotype:

IgG1

Clone:

B-N36

Conjugate:

Unconjugated

Formulation:

PBS containing 1% BSA and 0.09% sodium azide.

Purification:

Ion exchange Chromatography

Application:

FC, FS , Neutralizing

Application notes:

Neutralizes TRAIL induced apoptosis on HEL cell line

Storage/Stability:

Stable at +2-8°C for 12 months. For longer storage, freeze aliquots.