Mouse Anti-Human TRAIL-R2 / CD262 (Clone B-K29) mAb, Azide Free

Molecule:

TRAILR2/DR5

Synonyms:

Tumor necrosis factor receptor superfamily, member 10b, TRAIL-R2, Death receptor

Species:

Human

Cat. No.:

CDM234A pdf (datasheet)

Quantity/Size:

200 μg

Price:

$390.00 BUY

Concentration:

1 mg/ml

Description:

The monoclonal antibody recognizes the human protein TRAILR2/DR5, a member of the TNF-receptor superfamily. The receptor can be activated by tumor necrosis factorrelated apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal.

Entrez Symbol:

TNFRSF10B

Uniprot Name:

Tumor necrosis factor receptor superfamily member 10B

Uniprot ID:

O14763

Data PDF:

CDM234

Specificity:

Human TRAILR2/DR5, a 42-46 kDa protein

Host Species:

Mouse

Immunogen:

Recombinant human TRAIL R2/Fc chimera

Isotype:

IgG1 Kappa light chain

Clone:

B-K29

Formulation:

Sterile-filtered PBS, treated to remove endotoxins. Carrier and preservative free.

Purification:

Affinity chromatography

Application:

ELISA, FC, FS

Application notes:

Neutralizes TRAIL induced apoptosis of U937 cells line

Storage/Stability:

Stable at 2-8°C for 12 months. For longer storage freeze in working aliquots at -20 to -80°C. Avoid repeated freeze-thaw cycles.