Mouse Anti-Human TRAILR3 / CD263 (Clone B-D44) mAb, Azide Free

Molecule:

TRAILR3/DCR1

Synonyms:

Tumor necrosis factor receptor superfamily member 10C, TNF-related apoptosis-inducing ligand receptor 3, TRAIL Receptor 3, TRAIL receptor without an intracellular domain, Decoy TRAIL receptor without death domain, Decoy receptor 1, DcR1

Species:

Human

Cat. No.:

CDM238A pdf (datasheet)

Quantity/Size:

200 μg

Price:

$390.00 BUY

Concentration:

1 mg/ml

Description:

The monoclonal antibody recognizes the protein TRAILR3, a member of the TNFreceptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis.

Entrez Symbol:

TNFRSF10C

Uniprot Name:

Tumor necrosis factor receptor superfamily member 10C

Uniprot ID:

O14798

Data PDF:

CDM238

Specificity:

Recognizes TRAILR3/CD263, a 75.90 kDa protein

Host Species:

Mouse

Immunogen:

Recombinant human TRAIL R3/Fc chimera

Isotype:

IgG1 Kappa light chain

Clone:

B-D44

Formulation:

Sterile filtered PBS, carrier and preservative free.

Purification:

Affinity chromatography

Application:

FC, FS

Application notes:

Inhibits TRAIL binding to TRAIL R3

Storage/Stability:

Store at 2-8°C for up to 1 year or in working aliquots at -20°C to -80oC. Avoid repeated freeze-thaw cycles.