Mouse Anti-Human p53 (Clone B-P3) mAb, Azide Free

Molecule:

p53/TP53

Synonyms:

Cellular tumor antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53

Species:

Human

Cat. No.:

CDM072B pdf (datasheet)

Quantity/Size:

500 μg

Price:

$650.00 BUY

Concentration:

1 mg/ml

Description:

Tumor protein p53 is a multi-functional transcription factor that regulates cellular decisions regarding proliferation, cell cycle arrest, and apoptosis. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy. p53 is mutated in over 50% of human cancers.

Entrez Symbol:

TP53

Uniprot Name:

Cellular tumor antigen p53

Uniprot ID:

P04637

Data PDF:

CDM072

Specificity:

Recognizes wild type and mutant p53, cross-reacts with p53 in other primates. The epitope is within residues 18-30 of human p53.

Host Species:

Mouse

Immunogen:

Recombinant p53 protein

Isotype:

IgG2a kappa light chain

Clone:

B-P3

Formulation:

Sterile-filtered PBS, carrier and preservative free.

Purification:

Ion exchange chromatography

Application:

ELISA, FC, IHC-F, IHC-P, IP , WB

Application notes:

Suitable for intra-cytoplasmic flow cytometry.

Storage/Stability:

Store at 2-8°C for up to 1 year or in working aliquots at -20°C to -80oC. Avoid repeated freeze-thaw cycles.