Mouse Anti-Rat IL-13 (Clone A130D12G51E4) mAb

Molecule:

IL-13

Synonyms:

IL-13, T-cell activation protein P600

Cat. No.:

CMI173 pdf (datasheet)

Quantity/Size:

0.5 mg

Price:

$640.00 BUY

Concentration:

1.0 mg/ml

Description:

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.

Entrez Symbol:

Il13

Uniprot Name:

Interleukin 13

Uniprot ID:

P42203

Data PDF:

CMI173

Specificity:

Recognizes Recombinant and Native Rat IL-13.

Host Species:

Mouse

Immunogen:

Recombinant Rat IL13

Clone:

A130D12G51E4

Formulation:

Sterile filtered PBS, carrier and preservative free.

Application:

ELISA, FC, IHC, WB

Storage/Stability:

Store in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.