Mouse Cannabinoid 1 Receptor

Synonyms:

Cnr1

Cat. No.:

CSM1036PR pdf (datasheet)

Quantity/Size:

50 µg

Price:

$8,780.00 BUY

Description:

The cannabinoid type 1 receptor is a G protein-coupled receptor located in the central and peripheral nervous system. It is activated by the endocannabinoid neurotransmitters anandamide and 2-arachidonoylglycerol and by plant and synthetic cannabinoids, including the principle psychoactive constituent of marijuana - THC (tetrahydrocannabinol). Upon activation, Cnr1 receptor exhibits its effects mainly through activation of Gi, which decreases intracellular cAMP concentration by inhibiting its production enzyme, adenylate cyclase, and increases mitogen-activated protein kinase (MAP kinase) concentration. The receptor is available in the following formats: stable over-expression cell line, membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions are available.

Uniprot ID:

P47746

Data PDF:

CSM1036