Native Human Alpha-Fetoprotein, High Purity

Molecule:

AFP

Synonyms:

AFP, alpha-fetoglobulin, alpha-1-fetoprotein

Species:

Human

Cat. No.:

CS070A pdf (datasheet)

Quantity/Size:

100 μg

Price:

$150.00 BUY

Description:

AFP is the most abundant plasma protein found in the human fetus and thought to be the fetal analog of serum albumin. AFP binds to copper, nickel, fatty acids and bilirubin and is found in monomeric, dimeric and trimeric forms. Measurement of AFP has two clinical contexts: measurement in maternal blood or amniotic fluid as a screening test for certain developmental abnormalities such as aneuploidy, and for elevated serum AFP level in people with certain tumors. It is used as a biomarker to follow the progress of the disease.

Entrez Symbol:

AFP

Uniprot Name:

Alpha-fetoprotein

Uniprot ID:

P02771

Data PDF:

CS070

Source:

Human Serum

Molecular Weight:

approximately 68 kDa

Formulation:

Lyophilized from 50 mM ammonium bicarbonate.

Purity:

> 95% by SDS-PAGE Native PAGE shows one dark and two light bands occurring at ~68kDa. This correlates to the presence of three AFP isoforms (AFP-L1, AFP-L2, and AFP-L3) in physiological proportion. SDS-PAGE analysis may also reveal AFP dimers or trimers

Reconstitution:

Reconstitute with neutral pH buffer of choice.

Storage/Stability:

2-8°C for short term storage. Store as supplied for up to 1 year at -20°C to -80°C. Upon reconstitution, prepare working aliquots and store at -20°C to -80°C. Avoid repeated freeze/thaw cycles.